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GPRC6A Mediates the Effects of l-Arginine on Insulin Secretion in Mouse Pancreatic Islets

l-Arginine (l-Arg) is an insulin secretagogue, but the molecular mechanism whereby it stimulates insulin secretion from β-cells is not known. The possibility that l-Arg regulates insulin secretion through a G protein-coupled receptor (GPCR)-mediated mechanism is suggested by the high expression of t...

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Autores principales: Pi, Min, Wu, Yunpeng, Lenchik, Nataliya I, Gerling, Ivan, Quarles, L. Darryl
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512028/
https://ncbi.nlm.nih.gov/pubmed/22872579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1301
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