A Potential Role of Progestin-Induced Laminin-5/α6-Integrin Signaling in the Formation of Side Branches in the Mammary Gland

Mammary organoids from adult mice produce tubules, analogous to mammary ducts in vivo, in response to hepatocyte growth factor (HGF) when cultured in collagen gels. The combination of HGF plus progestin (R5020) causes reduced tubule number and length. We hypothesized that the inhibitory effect on tu...

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Detalhes bibliográficos
Main Authors: Meyer, Gabriele, Leipprandt, Jeffrey, Xie, Jianwei, Aupperlee, Mark D., Haslam, Sandra Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Reproduction-Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512027/
https://ncbi.nlm.nih.gov/pubmed/22910029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1518
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