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Downregulation of gastrokine-1 in gastric cancer tissues and restoration of its expression induced gastric cancer cells to apoptosis

BACKGROUND: Gastrokine-1 (GKN1), a secreted protein, is specifically expressed in gastric mucosa to protect and maintain the integrity of gastric epithelium. The present study investigated differential expression of GKN1 in normal, precancerous, and cancerous gastric tissues, and explored the biolog...

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Bibliografiske detaljer
Main Authors: Mao, Wei, Chen, Jie, Peng, Tie-Li, Yin, Xiao-Fei, Chen, Lian-Zhou, Chen, Min-Hu
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511871/
https://ncbi.nlm.nih.gov/pubmed/22621392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-49
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