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Comparative analysis of the biosynthetic systems for fungal bicyclo[2.2.2]diazaoctane indole alkaloids: the (+)/(−)-notoamide, paraherquamide and malbrancheamide pathways

The biosynthesis of fungal bicyclo[2.2.2]diazaoctane indole alkaloids with a wide spectrum of biological activities have attracted increasing interest. Their intriguing mode of assembly has long been proposed to feature a non-ribosomal peptide synthetase, a presumed intramolecular Diels-Alderase, a...

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Main Authors: Li, Shengying, Anand, Krithika, Tran, Hong, Yu, Fengan, Finefield, Jennifer M., Sunderhaus, James D., McAfoos, Timothy J., Tsukamoto, Sachiko, Williams, Robert M., Sherman, David H.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511817/
https://ncbi.nlm.nih.gov/pubmed/23213353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2MD20029E
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