Deletion of Orai1 Alters Expression of Multiple Genes during Osteoclast and Osteoblast Maturation

Store-operated Ca(2+) entry (SOCE) is a major Ca(2+) influx pathway in most non-excitable cell types and Orai1 was recently identified as an essential pore-subunit of SOCE channels. Here we investigate the physiological role of Orai1 in bone homeostasis using Orai1-deficient mice (Orai1(−/−)). Orai1...

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Bibliografiset tiedot
Päätekijät: Hwang, Sung-Yong, Foley, Julie, Numaga-Tomita, Takuro, Petranka, John G., Bird, Gary S., Putney, James W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511630/
https://ncbi.nlm.nih.gov/pubmed/23122304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2012.10.001
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