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Genotoxic Agents Promote the Nuclear Accumulation of Annexin A2: Role of Annexin A2 in Mitigating DNA Damage

Annexin A2 is an abundant cellular protein that is mainly localized in the cytoplasm and plasma membrane, however a small population has been found in the nucleus, suggesting a nuclear function for the protein. Annexin A2 possesses a nuclear export sequence (NES) and inhibition of the NES is suffici...

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Main Authors: Madureira, Patricia A., Hill, Richard, Lee, Patrick W. K., Waisman, David M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511559/
https://ncbi.nlm.nih.gov/pubmed/23226323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050591
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