Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms

Kaiso is the first member of the POZ family of zinc finger transcription factors reported to bind DNA with dual-specificity in both a sequence- and methyl-CpG-specific manner. Here, we report that Kaiso associates with and regulates the cyclin D1 promoter via the consensus Kaiso binding site (KBS),...

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Detalhes bibliográficos
Main Authors: Donaldson, Nickett S., Pierre, Christina C., Anstey, Michelle I., Robinson, Shaiya C., Weerawardane, Sonali M., Daniel, Juliet M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511522/
https://ncbi.nlm.nih.gov/pubmed/23226276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050398
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