Induction of cross-protection against influenza A virus by DNA prime-intranasal protein boost strategy based on nucleoprotein

BACKGROUND: The highly conserved nucleoprotein (NP) is an internal protein of influenza virus and is capable of inducing cross-protective immunity against different influenza A viruses, making it a main target of universal influenza vaccine. In current study, we characterized the immune response ind...

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Hauptverfasser: Luo, Jian, Zheng, Dan, Zhang, Wenjie, Fang, Fang, Wang, Hanzhong, Sun, Ying, Ding, Yahong, Xu, Chengfei, Chen, Quanjiao, Zhang, Hongbo, Huang, Ding, Sun, Bing, Chen, Ze
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2012
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511278/
https://ncbi.nlm.nih.gov/pubmed/23173785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-286
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