Hepatitis C Virus Mediated Changes in miRNA-449a Modulates Inflammatory Biomarker YKL40 through Components of the NOTCH Signaling Pathway

Liver disease due to hepatitis C virus (HCV) infection is an important health problem worldwide. HCV induced changes in microRNAs (miRNA) are shown to mediate inflammation leading to liver fibrosis. Gene expression analyses identified dysregulation of miRNA-449a in HCV patients but not in alcoholic...

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Main Authors: Sarma, Nayan J., Tiriveedhi, Venkataswarup, Subramanian, Vijay, Shenoy, Surendra, Crippin, Jeffrey S., Chapman, William C., Mohanakumar, Thalachallour
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511274/
https://ncbi.nlm.nih.gov/pubmed/23226395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050826
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