Prevalence of amino acid mutations in hepatitis C virus core and NS5B regions among Venezuelan viral isolates and comparison with worldwide isolates

BACKGROUND: Recent reports show that R70Q and L/C91M amino acid substitutions in the core from different hepatitis C virus (HCV) genotypes have been associated with variable responses to interferon (IFN) and ribavirin (RBV) therapy, as well to an increase of hepatocellular carcinoma (HCC) risk, live...

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Bibliografiske detaljer
Main Authors: Jaspe, Rossana C, Sulbarán, Yoneira F, Sulbarán, Maria Z, Loureiro, Carmen L, Rangel, Hector R, Pujol, Flor H
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511240/
https://ncbi.nlm.nih.gov/pubmed/22995142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-214
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