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Bioreducible and acid-labile poly(amido amine)s for efficient gene delivery

Intracellular processes, including endosomal escape and intracellular release, are efficiency-determining steps in achieving successful gene delivery. It has been found that the presence of acid-labile units in polymers can facilitate endosomal escape and that the presence of reducible units in poly...

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Hlavní autoři: Yu, Zhi-Qiang, Yan, Jun-Jie, You, Ye-Zi, Zhou, Qing-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511192/
https://ncbi.nlm.nih.gov/pubmed/23209367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S37334
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