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A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays

BACKGROUND: Hyperhomocysteinemia as a consequence of the MTHFR 677 C > T variant is associated with cardiovascular disease and stroke. Another factor that can potentially contribute to these disorders is a depleted nitric oxide level, which can be due to the presence of eNOS +894 G > T and eNO...

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Autori principali: Loo, Keat Wei, Griffiths, Lyn Robyn, Gan, Siew Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511178/
https://ncbi.nlm.nih.gov/pubmed/22594584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-34
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