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Phleboviruses encapsidate their genomes by sequestering RNA bases

Rift Valley fever and Toscana viruses are human pathogens for which no effective therapeutics exist. These and other phleboviruses have segmented negative-sense RNA genomes that are sequestered by a nucleocapsid protein (N) to form ribonucleoprotein (RNP) complexes of irregular, asymmetric structure...

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Detalhes bibliográficos
Main Authors: Raymond, Donald D., Piper, Mary E., Gerrard, Sonja R., Skiniotis, Georgios, Smith, Janet L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511139/
https://ncbi.nlm.nih.gov/pubmed/23129612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213553109
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