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Chromatin remodeling by the CHD7 protein is impaired by mutations that cause human developmental disorders
Mutations in the CHD7 gene cause human developmental disorders including CHARGE syndrome. Genetic studies in model organisms have further established CHD7 as a central regulator of vertebrate development. Functional analysis of the CHD7 protein has been hampered by its large size. We used a dual-tag...
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| Asıl Yazarlar: | , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511097/ https://ncbi.nlm.nih.gov/pubmed/23134727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213825109 |
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