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STING manifests self DNA-dependent inflammatory disease
Inflammatory autoimmune diseases such as systemic lupus erythematosus (SLE) and polyarthritis are characterized by chronic cytokine overproduction, suggesting that the stimulation of host innate immune responses, speculatively by persistent infection or self nucleic acids, plays a role in the manife...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
National Academy of Sciences
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511090/ https://ncbi.nlm.nih.gov/pubmed/23132945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215006109 |
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