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STING manifests self DNA-dependent inflammatory disease

Inflammatory autoimmune diseases such as systemic lupus erythematosus (SLE) and polyarthritis are characterized by chronic cytokine overproduction, suggesting that the stimulation of host innate immune responses, speculatively by persistent infection or self nucleic acids, plays a role in the manife...

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Bibliographic Details
Main Authors: Ahn, Jeonghyun, Gutman, Delia, Saijo, Shinobu, Barber, Glen N.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511090/
https://ncbi.nlm.nih.gov/pubmed/23132945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215006109
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