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STING manifests self DNA-dependent inflammatory disease

Inflammatory autoimmune diseases such as systemic lupus erythematosus (SLE) and polyarthritis are characterized by chronic cytokine overproduction, suggesting that the stimulation of host innate immune responses, speculatively by persistent infection or self nucleic acids, plays a role in the manife...

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Bibliografiske detaljer
Main Authors: Ahn, Jeonghyun, Gutman, Delia, Saijo, Shinobu, Barber, Glen N.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511090/
https://ncbi.nlm.nih.gov/pubmed/23132945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1215006109
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