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MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers

Toll-like receptor (TLR) signaling is one of the most important signaling cascades of the innate immune system of vertebrates. Studies in invertebrates have focused on the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans, and there is little information regarding the evoluti...

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Detalhes bibliográficos
Main Authors: Franzenburg, Sören, Fraune, Sebastian, Künzel, Sven, Baines, John F., Domazet-Lošo, Tomislav, Bosch, Thomas C. G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511086/
https://ncbi.nlm.nih.gov/pubmed/23112184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213110109
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