Watching a signaling protein function in real time via 100-ps time-resolved Laue crystallography

To understand how signaling proteins function, it is crucial to know the time-ordered sequence of events that lead to the signaling state. We recently developed on the BioCARS 14-IDB beamline at the Advanced Photon Source the infrastructure required to characterize structural changes in protein crys...

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Autors principals: Schotte, Friedrich, Cho, Hyun Sun, Kaila, Ville R. I., Kamikubo, Hironari, Dashdorj, Naranbaatar, Henry, Eric R., Graber, Timothy J., Henning, Robert, Wulff, Michael, Hummer, Gerhard, Kataoka, Mikio, Anfinrud, Philip A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511082/
https://ncbi.nlm.nih.gov/pubmed/23132943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210938109
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