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A Wittig-olefination–Claisen-rearrangement approach to the 3-methylquinoline-4-carbaldehyde synthesis

Efficient syntheses are described for the synthetically important 3-methylquinoline-4-carbaldehydes 6a–h from o-nitrobenzaldehydes 1a–h employing a Wittig-olefination–Claisen-rearrangement protocol. The Wittig reaction of o-nitrobenzaldehydes with crotyloxymethylene triphenylphosphorane afforded cro...

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Hlavní autoři: Kulkarni, Mukund G, Desai, Mayur P, Birhade, Deekshaputra R, Shaikh, Yunus B, Dhatrak, Ajit N, Gannimani, Ramesh
Médium: Artigo
Jazyk:Inglês
Vydáno: Beilstein-Institut 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511006/
https://ncbi.nlm.nih.gov/pubmed/23209506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.8.197
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