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Essential role of calcium in cellular internalization of Pseudomonas toxin.

Pseudomonas exotoxin (PE) has been shown previously to enter mouse LM cells by receptor-mediated endocytosis, to block protein synthesis, and to cause cell death. The requirement for the divalent cation calcium in the binding and internalization of PE was examined. Biochemical studies showed that de...

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Autors principals: Fitzgerald, D, Morris, R E, Saelinger, C B
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC351100/
https://ncbi.nlm.nih.gov/pubmed/6799408
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