Astrocyte-induced Synaptogenesis Is Mediated by Transforming Growth Factor β Signaling through Modulation of d-Serine Levels in Cerebral Cortex Neurons

Assembly of synapses requires proper coordination between pre- and postsynaptic elements. Identification of cellular and molecular events in synapse formation and maintenance is a key step to understand human perception, learning, memory, and cognition. A key role for astrocytes in synapse formation...

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Bibliographische Detailangaben
Hauptverfasser: Diniz, Luan Pereira, Almeida, Juliana Carvalho, Tortelli, Vanessa, Vargas Lopes, Charles, Setti-Perdigão, Pedro, Stipursky, Joice, Kahn, Suzana Assad, Romão, Luciana Ferreira, de Miranda, Joari, Alves-Leon, Soniza Vieira, de Souza, Jorge Marcondes, Castro, Newton G., Panizzutti, Rogério, Gomes, Flávia Carvalho Alcantara
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Neurobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510841/
https://ncbi.nlm.nih.gov/pubmed/23055518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.380824
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