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Retroviral Integrase Proteins and HIV-1 DNA Integration

Retroviral integrases catalyze two reactions, 3′-processing of viral DNA ends, followed by integration of the processed ends into chromosomal DNA. X-ray crystal structures of integrase-DNA complexes from prototype foamy virus, a member of the Spumavirus genus of Retroviridae, have revealed the struc...

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Autores principales: Krishnan, Lavanya, Engelman, Alan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510789/
https://ncbi.nlm.nih.gov/pubmed/23043109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R112.397760
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