Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans

Leukocyte telomere length (LTL) is associated with a number of common age-related diseases and is a heritable trait. Previous genome-wide association studies (GWASs) identified two loci on chromosomes 3q26.2 (TERC) and 10q24.33 (OBFC1) that are associated with the inter-individual LTL variation. We...

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Bibliografiset tiedot
Päätekijät: Mangino, Massimo, Hwang, Shih-Jen, Spector, Timothy D., Hunt, Steven C., Kimura, Masayuki, Fitzpatrick, Annette L., Christiansen, Lene, Petersen, Inge, Elbers, Clara C., Harris, Tamara, Chen, Wei, Srinivasan, Sathanur R., Kark, Jeremy D., Benetos, Athanase, El Shamieh, Said, Visvikis-Siest, Sophie, Christensen, Kaare, Berenson, Gerald S., Valdes, Ana M., Viñuela, Ana, Garcia, Melissa, Arnett, Donna K., Broeckel, Ulrich, Province, Michael A., Pankow, James S., Kammerer, Candace, Liu, Yongmei, Nalls, Michael, Tishkoff, Sarah, Thomas, Fridtjof, Ziv, Elad, Psaty, Bruce M., Bis, Joshua C., Rotter, Jerome I., Taylor, Kent D., Smith, Erin, Schork, Nicholas J., Levy, Daniel, Aviv, Abraham
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2012
Aiheet:
Association Studies Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510758/
https://ncbi.nlm.nih.gov/pubmed/23001564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds382
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