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NdgR, a Common Transcriptional Activator for Methionine and Leucine Biosynthesis in Streptomyces coelicolor

We show here that NdgR, a known transcriptional activator of isopropylmalate dehydratase in actinomycetes, may have other targets in the cell. An in-frame deletion mutant of ndgR showed unexpectedly poor growth in defined minimal medium even in the presence of leucine. To our surprise, it was supple...

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Autori principali: Kim, Songhee H., Lee, Bo-Rahm, Kim, Ji-Nu, Kim, Byung-Gee
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510589/
https://ncbi.nlm.nih.gov/pubmed/23065973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00695-12
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