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Distant Activation of Transcription: Mechanisms of Enhancer Action

Enhancers are regulatory DNA sequences that activate transcription over long distances. Recent studies revealed a widespread role of distant activation in eukaryotic gene regulation and in development of various human diseases, including cancer. Genomic and gene-targeted studies of enhancer action r...

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Bibliografiske detaljer
Main Authors: Kulaeva, Olga I., Nizovtseva, Ekaterina V., Polikanov, Yury S., Ulianov, Sergei V., Studitsky, Vasily M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510544/
https://ncbi.nlm.nih.gov/pubmed/23045397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01127-12
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