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Iron-Induced Dissociation of the Aft1p Transcriptional Regulator from Target Gene Promoters Is an Initial Event in Iron-Dependent Gene Suppression

Aft1p is an iron-responsive transcriptional activator that plays a central role in the regulation of iron metabolism in Saccharomyces cerevisiae. Aft1p is regulated by accelerated nuclear export in the presence of iron, mediated by Msn5p. However, the transcriptional activity of Aft1p is suppressed...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ueta, Ryo, Fujiwara, Naoko, Iwai, Kazuhiro, Yamaguchi-Iwai, Yuko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510542/
https://ncbi.nlm.nih.gov/pubmed/23045394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00726-12
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