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Regulation of Chaperone Effects on a Yeast Prion by Cochaperone Sgt2

Yeast prions, based on self-seeded highly ordered fibrous aggregates (amyloids), serve as a model for human amyloid diseases. Propagation of yeast prions depends on the balance between chaperones of the Hsp100 and Hsp70 families. The yeast prion [PSI(+)] can be eliminated by an excess of the chapero...

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Detalhes bibliográficos
Main Authors: Kiktev, Denis A., Patterson, Jesse C., Müller, Susanne, Bariar, Bhawana, Pan, Tao, Chernoff, Yury O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510541/
https://ncbi.nlm.nih.gov/pubmed/23045389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00875-12
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