Structure of Actin-related protein 8 and its contribution to nucleosome binding

Nuclear actin-related proteins (Arps) are subunits of several chromatin remodelers, but their molecular functions within these complexes are unclear. We report the crystal structure of the INO80 complex subunit Arp8 in its ATP-bound form. Human Arp8 has several insertions in the conserved actin fold...

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Detalhes bibliográficos
Main Authors: Gerhold, Christian B., Winkler, Duane D., Lakomek, Kristina, Seifert, Florian U., Fenn, Sebastian, Kessler, Brigitte, Witte, Gregor, Luger, Karolin, Hopfner, Karl-Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510490/
https://ncbi.nlm.nih.gov/pubmed/22977180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks842
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