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A proposed consensus panel of organisms for determining evolutionary conservation of mt-tRNA point mutations
Assigning pathogenicity to mt-tRNA variants requires multiple strands of evidence. Evolutionary conservation is often considered mandatory, but lack of a standard panel of organisms to assess conservation complicates comparison between reports and undermines the value of conservation-based evidence....
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3510436/ https://ncbi.nlm.nih.gov/pubmed/22781547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2012.06.009 |
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