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A proposed consensus panel of organisms for determining evolutionary conservation of mt-tRNA point mutations

Assigning pathogenicity to mt-tRNA variants requires multiple strands of evidence. Evolutionary conservation is often considered mandatory, but lack of a standard panel of organisms to assess conservation complicates comparison between reports and undermines the value of conservation-based evidence....

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Detaylı Bibliyografya
Asıl Yazarlar: Yarham, John W., McFarland, Robert, Taylor, Robert W., Elson, Joanna L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510436/
https://ncbi.nlm.nih.gov/pubmed/22781547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mito.2012.06.009
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