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Characterization of the activity and expression of arginine decarboxylase in human and animal Chlamydia pathogens

Chlamydia pneumoniaeencodes a functional arginine decarboxylase (ArgDC), AaxB, that activates upon self-cleavage and converts L-arginine to agmatine. In contrast, most Chlamydia trachomatis serovars carry a missense or nonsense mutation in aaxB abrogating activity. The G115R missense mutation was no...

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Main Authors: Bliven, Kimberly A., Fisher, Derek J., Maurelli, Anthony T.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510315/
https://ncbi.nlm.nih.gov/pubmed/23043454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1574-6968.12021
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