Identification of Pigment Epithelium-Derived Factor as an Adipocyte-Derived Inflammatory Factor

Obesity is a major risk factor for insulin resistance, type 2 diabetes mellitus and cardiovascular disease. The pathophysiology of obesity is associated with chronic low-grade inflammation. Adipose tissue in obesity is significantly infiltrated by macrophages that secrete cytokines. The mechanisms o...

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Main Authors: Chavan, Sangeeta S, Hudson, LaQueta K, Li, Jian Hua, Ochani, Mahendar, Harris, Yael, Patel, Nirav B, Katz, David, Scheinerman, Joshua A, Pavlov, Valentin A, Tracey, Kevin J
Format: Artigo
Sprog:Inglês
Udgivet: ScholarOne 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510299/
https://ncbi.nlm.nih.gov/pubmed/22714715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00156
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