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CCR5 Antagonism Impacts Vaccination Response and Immune Profile in HIV-1 Infection

Maraviroc (MVC) is the first licensed antiretroviral therapeutic agent to target a host cell surface molecule, and successful HIV-1 entry blockade by this C-C chemokine receptor type 5 (CCR5)-antagonist potentiates immunomodulation. We hypothesized that MVC intensification impacts immunization respo...

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Main Authors: Westrop, Samantha J, Moyle, Graeme, Jackson, Akil, Nelson, Mark, Mandalia, Sundhiya, Imami, Nesrina
Format: Artigo
Jezik:Inglês
Izdano: ScholarOne 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510292/
https://ncbi.nlm.nih.gov/pubmed/22875102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2012.00206
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