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Dual Inhibition of PI3K/Akt/mTOR Pathway and Role of Autophagy in Non-Small Cell Lung Cancer Cells

BACKGROUND: The phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling axis has emerged as a novel target for cancer therapy. Agents that inhibit this pathway are currently under development for lung cancer treatment. In the present study, we have tested whether dual inh...

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Autors principals: Jeong, Eun-Hui, Choi, Hyeong Sim, Lee, Tae-Gul, Kim, Hye-Ryoun, Kim, Cheol Hyeon
Format: Artigo
Idioma:Inglês
Publicat: The Korean Academy of Tuberculosis and Respiratory Diseases 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510285/
https://ncbi.nlm.nih.gov/pubmed/23227075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4046/trd.2012.72.4.343
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