Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection

BACKGROUND: The bacterial pathogen Salmonella causes worldwide disease. A major route of intestinal entry involves M cells, providing access to B cell-rich Peyer’s Patches. Primary human B cells phagocytose Salmonella typhimurium upon recognition by the specific surface Ig receptor (BCR). As it is u...

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Main Authors: Souwer, Yuri, Griekspoor, Alexander, de Wit, Jelle, Martinoli, Chiara, Zagato, Elena, Janssen, Hans, Jorritsma, Tineke, Bar-Ephraïm, Yotam E., Rescigno, Maria, Neefjes, Jacques, van Ham, S. Marieke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510171/
https://ncbi.nlm.nih.gov/pubmed/23209805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050667
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