The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infection. Here we resolve the major genetic influences for NPC incidence using a genome-wide association study (GWAS), independent cohort replication, and high-resolution molecular HLA class I gene typing i...

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Detalhes bibliográficos
Main Authors: Tang, Minzhong, Lautenberger, James A., Gao, Xiaojiang, Sezgin, Efe, Hendrickson, Sher L., Troyer, Jennifer L., David, Victor A., Guan, Li, Mcintosh, Carl E., Guo, Xiuchan, Zheng, Yuming, Liao, Jian, Deng, Hong, Malasky, Michael, Kessing, Bailey, Winkler, Cheryl A., Carrington, Mary, dé The, Guy, Zeng, Yi, O'Brien, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510037/
https://ncbi.nlm.nih.gov/pubmed/23209447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003103
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