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Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

Genome-wide association studies (GWAS) have identified loci reproducibly associated with pulmonary diseases; however, the molecular mechanism underlying these associations are largely unknown. The objectives of this study were to discover genetic variants affecting gene expression in human lung tiss...

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Autori principali: Hao, Ke, Bossé, Yohan, Nickle, David C., Paré, Peter D., Postma, Dirkje S., Laviolette, Michel, Sandford, Andrew, Hackett, Tillie L., Daley, Denise, Hogg, James C., Elliott, W. Mark, Couture, Christian, Lamontagne, Maxime, Brandsma, Corry-Anke, van den Berge, Maarten, Koppelman, Gerard, Reicin, Alise S., Nicholson, Donald W., Malkov, Vladislav, Derry, Jonathan M., Suver, Christine, Tsou, Jeffrey A., Kulkarni, Amit, Zhang, Chunsheng, Vessey, Rupert, Opiteck, Greg J., Curtis, Sean P., Timens, Wim, Sin, Don D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510026/
https://ncbi.nlm.nih.gov/pubmed/23209423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003029
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