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Spatiotemporal Regulation of an Hcn4 Enhancer Defines a Role for Mef2c and HDACs in Cardiac Electrical Patterning

Regional differences in cardiomyocyte automaticity permit the sinoatrial node (SAN) to function as the leading cardiac pacemaker and the atrioventricular (AV) junction as a subsidiary pacemaker. The regulatory mechanisms controlling the distribution of automaticity within the heart are not understoo...

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Detalhes bibliográficos
Main Authors: Vedantham, Vasanth, Evangelista, Melissa, Huang, Yu, Srivastava, Deepak
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510001/
https://ncbi.nlm.nih.gov/pubmed/23085412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.10.017
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