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Crystallization and preliminary X-ray analysis of the open form of human ecto-5′-nucleotidase (CD73)
Eukaryotic ecto-5′-nucleotidase (e5NT) catalyses the hydrolysis of extracellular AMP to adenosine and plays a pivotal role in switching on adenosine signalling via the P1 receptors of the purinergic signalling pathway. With such an important regulatory role, e5NT has become an appealing new drug tar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509985/ https://ncbi.nlm.nih.gov/pubmed/23192044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112045447 |
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