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In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland

Adrenal and gonadal steroids are essential for life and reproduction. The orphan nuclear receptor SF1 (NR5A1) has been shown to regulate the expression of enzymes involved in steroid production in vitro. However, the in vivo role of this transcription factor in steroidogenesis has not been elucidate...

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Détails bibliographiques
Auteurs principaux: Buaas, F. William, Gardiner, Jennifer R., Clayton, Sally, Val, Pierre, Swain, Amanda
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509722/
https://ncbi.nlm.nih.gov/pubmed/23136395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087247
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