Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-β Impairs Base Excision Repair in Human Neuroblastoma Cells

Alzheimer’s disease (AD) is the leading cause of dementia in developed countries. It is characterized by two major pathological hallmarks, one of which is the extracellular aggregation of the neurotoxic peptide amyloid-β (Aβ), which is known to generate oxidative stress. In this study, we showed tha...

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Bibliographic Details
Main Authors: Forestier, Anne, Douki, Thierry, Sauvaigo, Sylvie, De Rosa, Viviana, Demeilliers, Christine, Rachidi, Walid
Format: Artigo
Language:Inglês
Published: Molecular Diversity Preservation International (MDPI) 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509609/
https://ncbi.nlm.nih.gov/pubmed/23203093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131114766
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