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Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-β Impairs Base Excision Repair in Human Neuroblastoma Cells

Alzheimer’s disease (AD) is the leading cause of dementia in developed countries. It is characterized by two major pathological hallmarks, one of which is the extracellular aggregation of the neurotoxic peptide amyloid-β (Aβ), which is known to generate oxidative stress. In this study, we showed tha...

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Detalhes bibliográficos
Main Authors: Forestier, Anne, Douki, Thierry, Sauvaigo, Sylvie, De Rosa, Viviana, Demeilliers, Christine, Rachidi, Walid
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509609/
https://ncbi.nlm.nih.gov/pubmed/23203093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131114766
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