Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-β Impairs Base Excision Repair in Human Neuroblastoma Cells

Alzheimer’s disease (AD) is the leading cause of dementia in developed countries. It is characterized by two major pathological hallmarks, one of which is the extracellular aggregation of the neurotoxic peptide amyloid-β (Aβ), which is known to generate oxidative stress. In this study, we showed tha...

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Hlavní autoři: Forestier, Anne, Douki, Thierry, Sauvaigo, Sylvie, De Rosa, Viviana, Demeilliers, Christine, Rachidi, Walid
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Diversity Preservation International (MDPI) 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509609/
https://ncbi.nlm.nih.gov/pubmed/23203093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131114766
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