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Pathogenesis of Experimental Skin Infections Induced by Drug-Resistant Herpes Simplex Virus Mutants

The comparative analysis of the pathogenicity of a parental herpes simplex virus type 1 strain and its phosphonoacetic acid (PAA)-resistant and acyclovir (ACV)-resistant mutants showed marked differences among them. After orofacial skin inoculation of hairless mice the parental and PAA-resistant vir...

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Detalhes bibliográficos
Main Authors: Klein, Richard J., Friedman-Kien, Alvin E., DeStefano, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC350926/
https://ncbi.nlm.nih.gov/pubmed/6277789
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