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Apical acidity decreases inhibitory effect of omeprazole on Mg(2+) absorption and claudin-7 and -12 expression in Caco-2 monolayers

Clinical studies reported hypomagnesaemia in long-term omeprazole usage that was probably due to intestinal Mg(2+) wasting. Our previous report demonstrated the inhibitory effect of omeprazole on passive Mg(2+) transport across Caco-2 monolayers. The present study aimed to identify the underlying me...

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Detalhes bibliográficos
Main Authors: Thongon, Narongrit, Krishnamra, Nateetip
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509185/
https://ncbi.nlm.nih.gov/pubmed/22940736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.11.077
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