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Extraoral bitter taste receptors as mediators of off-target drug effects
We present a novel hypothesis that could explain many off-target effects of diverse pharmaceuticals. Specifically, we propose that any drug with a bitter taste could have unintended actions in the body through stimulation of extraoral type 2 taste receptors (T2Rs). T2Rs were first identified in the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3509062/ https://ncbi.nlm.nih.gov/pubmed/22964302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-215087 |
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