Non-Synonymous Polymorphisms in the FCN1 Gene Determine Ligand-Binding Ability and Serum Levels of M-Ficolin

BACKGROUND: The innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells. One such pattern-recognition molecule is M-ficolin, which is capable of activating the complement system through the...

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Main Authors: Ammitzbøll, Christian Gytz, Kjær, Troels Rønn, Steffensen, Rudi, Stengaard-Pedersen, Kristian, Nielsen, Hans Jørgen, Thiel, Steffen, Bøgsted, Martin, Jensenius, Jens Christian
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509001/
https://ncbi.nlm.nih.gov/pubmed/23209787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050585
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