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cAMP-dependent Mobilization of Intracellular Ca(2+) Stores by Activation of Ryanodine Receptors in Pancreatic β-Cells: A Ca(2+) SIGNALING SYSTEM STIMULATED BY THE INSULINOTROPIC HORMONE GLUCAGON-LIKE PEPTIDE-1-(7–37)

Glucagon-like peptide-1 (GLP-1) is an intestinally derived insulinotropic hormone currently under investigation for use as a novel therapeutic agent in the treatment of type 2 diabetes mellitus. In vitro studies of pancreatic islets of Langerhans demonstrated that GLP-1 interacts with specific β-cel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Holz, George G., Leech, Colin A., Heller, R. Scott, Castonguay, Maurice, Habener, Joel F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508791/
https://ncbi.nlm.nih.gov/pubmed/10318832
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