Aldehyde dehydrogenase 1A1 confers intrinsic and acquired resistance to gemcitabine in human pancreatic adenocarcinoma MIA PaCa-2 cells

Gemcitabine (GEM) is the front-line standard chemotherapy used for the treatment of pancreatic cancer; however, chemoresistance to GEM remains the major obstacle to the successful control of this disease. Both the expression levels and activity of aldehyde dehydrogenase 1A1 (ALDH1A1) are important f...

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Hlavní autoři: DUONG, HONG-QUAN, HWANG, JAE SEOK, KIM, HEE JEONG, KANG, HYO JIN, SEONG, YEON-SUN, BAE, INSOO
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2012
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508685/
https://ncbi.nlm.nih.gov/pubmed/22710732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1516
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