Skeletal muscle molecular alterations precede whole-muscle dysfunction in NYHA Class II heart failure patients

BACKGROUND: Heart failure (HF), a debilitating disease in a growing number of adults, exerts structural and neurohormonal changes in both cardiac and skeletal muscles. However, these alterations and their affected molecular pathways remain uncharacterized. Disease progression is known to transform s...

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Bibliographic Details
Main Authors: Godard, Michael P, Whitman, Samantha A, Song, Yao-Hua, Delafontaine, Patrice
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2012
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508558/
https://ncbi.nlm.nih.gov/pubmed/23204842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S37879
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