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The Pathogenesis of Systemic Lupus Erythematosus – An Update
Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells leading to production of pathogenic autoantibodies and tissue injury. Innate immune mechanisms are necessary for the aberrant adaptive immune responses in SLE....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3508331/ https://ncbi.nlm.nih.gov/pubmed/23131610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.10.004 |
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