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The Pathogenesis of Systemic Lupus Erythematosus – An Update

Systemic lupus erythematosus (SLE, lupus) is characterized by a global loss of self-tolerance with activation of autoreactive T and B cells leading to production of pathogenic autoantibodies and tissue injury. Innate immune mechanisms are necessary for the aberrant adaptive immune responses in SLE....

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Choi, Jinyoung, Kim, Sang Taek, Craft, Joe
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508331/
https://ncbi.nlm.nih.gov/pubmed/23131610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2012.10.004
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